cerebMAX All Natural Targeted Brain Support Optimize Cerebral Functions

$55.00

COMING SOON  Pharma Natural’s Natural Health Sciences Research & Development Laboratory especially formulated the key ingredients in cerebMAX for the express purpose of providing all-natural, nutrition-based support of the brain’s cognitive functions and its management and control of human emotions, motor skills, and sensory operations. Scientific research of all of the ingredients in cerebMAX have found them to potentially offer important benefits contributing to brain health and optimization of cerebral functions.The brain is subject to continuous degenerative forces caused by stress and environmental conditions, as well as the normal aging process. However, scientific research has found that, not only do our brain cells have built-in, self-healing systems that provide natural defenses against these ongoing threats; the human brain also has the ability to remodel or regenerate brain functions (plasticity).

 

These statements have not been evaluated by the Food and Drug Administration (FDA).
This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease.

Pharma Natural’s Natural Health Sciences Research & Development Laboratory especially formulated the key ingredients in cerebMAX for the express purpose of providing all-natural, nutrition-based support of the brain’s cognitive functions and its management and control of human emotions, motor skills, and sensory operations. Scientific research of all of the ingredients in cerebMAX have found them to potentially offer important benefits contributing to brain health and optimization of cerebral functions.The brain is subject to continuous degenerative forces caused by stress and environmental conditions, as well as the normal aging process. However, scientific research has found that, not only do our brain cells have built-in, self-healing systems that provide natural defenses against these ongoing threats; the human brain also has the ability to remodel or regenerate brain functions (plasticity).

 

These statements have not been evaluated by the Food and Drug Administration (FDA). This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease.

Vitamin D3  Calcitriol, the active form of Vitamin D, is arguably the most powerful hormone in the body. It has the ability to activate over 1,000 genes which is roughly 5% of the human genome. Scientists have linked this nutrient’s activity to a number of functions throughout the body, including the workings of the brain. Research suggests a strong link between vitamin D status and basic cognitive function, mood and overall mental health.

Higher Vitamin E intake is associated with healthy cognitive function. Vitamin E provides protection against free radicals, molecules that can damage cells, including brain cells, tissues and organs. Free radicals form as a result of normal body processes. They cause damage that shortens the life of your cells. Vitamin E is a powerful antioxidant that may help reduce free radical damage and slow the aging process of your cells, according to the National Institutes of Health (NIH).

Vitamin C is among the best vitamins for the brain. It aids in multiple functions in the brain. Improved Circulation: By helping to build collagen that keeps arteries flexible, vitamin C improves blood flow.  Increased blood flow delivers more oxygen and nutrients to your brain, keeping it properly nourished, enabling proper cognition and other brain functions.

B-Complex Vitamins When you think of the “B” in B Complex Vitamins , think B, for Brain. Imbalances of the major brain chemicals can significantly alter your mental health. The B-Complex Vitamins play an essential role in modulating brain chemicals.  An important role of B vitamins for brain health is the production of the neurotransmitters serotonin, dopamine and GABA.  Boosting your B vitamins intake can improve your neurotransmitter balance and your mental well-being. A serotonin deficiency can contribute to anxiety, insomnia, low self-esteem, negative thoughts, OCD and SAD (seasonal affective disorder). Without adequate GABA (gamma-aminobutyric acid), persons can be easily stressed, overstimulated and overwhelmed. Dopamine helps focus and concentration. Symptoms of a low dopamine level are low energy and motivation. B vitamins can improve energy levels and increase your tolerance to stress. B Vitamins with Folic Acid prevents mental decline. B6, B12 and folic acid (B9) are especially vital for brain health. Studies have shown that these vitamins work together to help prevent mental decline, dementia and Alzheimer’s disease.

A Special Note: A Very Common Deficiency: Vitamin B12. This is a very prevalent vitamin deficiency in the US. Vitamin B12 deficiency is a serious matter and should not be taken lightly. It can lead to a wide spectrum of mental disorders including memory loss, dementia, depression, and even measurable brain atrophy.

Folic Acid  Folates are important in the nervous system at all ages and there is growing evidence of their involvement in the ageing brain, especially in mood and cognitive function. Folates supports neurotransmitter synthesis — which in turn helps maintain cognitive abilities. Open and controlled treatment studies confirm an aetiological link with specific effects of the vitamin on mood, drive, initiative, alertness, concentration, psychomotor speed, and social activity. These observations are reinforced by the cognitive studies in otherwise healthy subjects, suggesting that low folate levels are associated with patterns of impairment.

Zinc is an essential mineral that plays a vital role in brain health. A zinc deficiency may have an effect on other nutrients that help the brain function. The Mayo Clinic reports that zinc supplements may benefit symptoms of hyperactivity, impulsivity, and social problems. Regarding brain-related cognition an improvement in cognition has been seen in stroke patients given zinc to complement their zinc insufficient diet. Zinc has been previously associated with an improvement in mood state and has mechanisms by which it can work Secondary to an improvement in overall mood, aggressive symptoms have been noted to be reduced with low dose zinc supplementation. Zinc deficiency is something that’s very common and can cause a number of health issues. It is estimated that about 75 percent of people  today are deficient in zinc and/or show display zinc deficiency symptoms. The top 2 causes of Zinc deficiency are 1. Stress. High levels of emotional stress can deplete zinc and zinc is a reparative mineral that the body needs to heal and repair the body, brain, skin and organs. 2. Overtraining: The second most common cause of zinc deficiency is over-exercise and overtraining. Triathletes, marathon runners and CrossFit athletes and persons engaged in high-intensity training (HITT) are some of the people that are most susceptible to a zinc deficiency.

Magnesium deficiency is one of the leading nutrient deficiencies in adults with an estimated 80 percent being deficient in this vital mineral. Magnesium is an essential dietary mineral, and the second most prevalent electrolyte in the human body.  A deficiency causes neural excitation, increases blood pressure and reduces glucose tolerance. Magnesium is vital for GABA function, an inhibitory neurotransmitter that produces serotonin. Certain hormones, including serotonin, regulated by magnesium are crucial for calming the brain and promoting relaxation, which is one reason why a magnesium deficiency can lead to sleeplessness or insomnia. Maintaining healthy magnesium levels is also associated with a protective effect against depression and ADHD. Initial scientific research into the effects of magnesium supplementation boosting physical performance is promising. Magnesium plays a critical role in brain function and mood, and low levels are linked to an increased risk of depression.

Selenium is an extremely important micronutrient that may be low in the diets of some modern populations, leading to chronic health problems. Selenium is key to one of the body’s primary antioxidants, glutathione peroxidase. This complex keeps the delicate polyunsaturated acids in cell membranes from getting oxidized (rancid). Proper amounts of glutathione peroxidase are necessary to protect cell membranes. A recent University of Otago study published in the prestigious Journal of Nutrition has found that selenium levels that are both too high in the body, and far worse, too low, can place young people at greater risk of depression, lower concentrations of selenium were found to be even more detrimental to these outcomes. Oxidative stress is believed to be involved in both the onset and the progression of neurological diseases like Parkinson’s, multiple sclerosis and Alzheimer’s disease. Several studies have shown that patients with Alzheimer’s disease have lower blood levels of selenium.  Additionally, some studies have shown that selenium in both food and supplements may improve memory in patients with Alzheimer’s disease.

MAX-BRAIN-16 Brain Power Blend, formulated by Pharma Natural’s Natural Health Sciences Research & Development Laboratory is a proprietary blend of natural substances, each having been found to aid brain functions and support healthy brain cells, including:

Phosphatidylcholine offers many different benefits for your brain. This nootropic compound is used to boost memory, enhance intellectual skills, increase concentration, and improve overall brain health. Phosphatidylcholine benefits are derived from the fact that it is a source of choline which is an essential nutrient necessary for proper brain function.  A large part of the volume of brain cells are comprised of Choline (in various forms) and it is incorporated in all neuron cell membranes.

Phosphatidylinositol is present in all tissues and cell types, especially brain tissue. Derivatives of this phospholipid serve as messenger molecules with the nervous system. Phosphatidylinositol is an important lipid, both as a key membrane constituent and as a participant in essential metabolic processes, both directly and via a number of metabolites. Phosphatidylinositol is especially abundant in brain tissue, where it can amount to 10% of the phospholipids. Phosphatidylinositol is involved in the phosphoinositide signal transduction system, one of the primary means for intercellular communication in the central nervous system. Investigators have begun to examine the effects of neurological and psychiatric diseases on the activity of the phosphoinositide system. Alzheimer’s disease has been studied to the greatest extent and a severe deficit in phosphoinositide signaling has been identified in most studies.

 

GABA is the most potent depressive neuroamine in human brains. It regulates many of the sedative actions in brain tissue and is critical for relaxation. GABA regulates unwanted firing of neurons not only in the brain, but in nerve connections to muscles and glands as well, in addition to improving sleep, it can also be useful in a wide array of situations including: calming nerves, improving mood and reducing anxiety.

Carnosine is a peptide the body uses to repair tissues and clear away toxins. It increases the energy output of cellular mitochondria.  Emerging research indicates that Carnosine can revive mitochondria. It can even rescue brain cells if their mitochondria have stopped functioning. Carnosine can reverse mitochondrial failure. Brain tissue naturally contains high levels of carnosine, which can reduce the oxidative, nitrosative, and glycemic stress to which the brain is especially vulnerable. Oxidation and glycation produce inflammation. Carnosine can preserve normal neuronal function, and helps minimize toxicity created by the high levels of metal ions that are present in certain areas of the brain.

Tyrosine benefits mental health in many ways. It’s a precursor to major neurotransmitters and can help with dopamine-related depression, ADHD, and extreme stress. Tyrosine is a naturally occurring compound of primary importance for mental health. It is a precursor to some of the most important brain chemicals and hormones. Tyrosine is an amino acid involved in the structure of almost every protein in the body. Tyrosine is one of the handful of conditional amino acids.  means that your body can usually make what it needs, but not always in adequate amounts. Stress, overwork, lack of sleep, illness, or eating too little protein can all increase your need for tyrosine. Tyrosine is a precursor to three important neurotransmitters: dopamine, epinephrine and norepinephrine. Neurotransmitters are chemicals that brain cells use to communicate with each other. They have profound effects on every aspect of your life.

Astaxanthin is primarily known for its immune boosting and anti-inflammatory properties. There is ample evidence that astaxanthin can reduce inflammation This is primarily due to anti-oxidant properties, which are said to promote the longevity of cells as well. Some studies suggest that these anti-inflammatory properties reduce cognitive deficits . Recent studies also show that astaxanthin can help to reduce signs of aging by increasing brain-derived neurotrophic factor (BDNF) and combating oxidative stress in the brain  BDNF are associated with neurogenesis and growth.

Carnitine, (as Acetyl l-carnitine), is an amino acid that helps the body produce energy. It is also a powerful antioxidant and crosses the blood-brain barrier where it both plays a role in the production of the neurotransmitter acetylcholine and supports healthy blood flow to the brain. Acetylcholine is integral to healthy memory, learning, computation, analysis, perception, and many other cognitive functions. Higher levels of acetylcholine may result in greater synaptic flexibility and memory formation, two indicators of healthy brain function. ALCAR is an excellent brain booster and natural antidepressant that works by increasing levels of both norepinephrine and serotonin. Norepinephrine deficiency is linked to a substantial number of mental health disorders.

Glutamic Acid, glutamine is one of 20 naturally occurring amino acids in dietary protein. In fact, L-glutamine is the most abundant amino acid in the bloodstream and makes up 30–35 percent of the amino acid nitrogen in your blood. It’s known as a conditionally essential amino acid because your body uses it in large amounts.  A precursor to the neurotransmitter glutamate in your brain, glutamine is key to boosting your brain health. Disruption of the glutamine-glutamate cycle can result in a number of brain problems, including Reye’s Syndrome, epilepsy, bipolar disorder, schizophrenia, anxiety, depression and alcohol addiction. Glutamine also provides brain-related anti-aging properties. Mitochondrial dysfunction causes abnormal increases in the neurotransmitter glutamate, putting the brain at risk.

PABA, para-aminobenzoic acid (or PABA) encourages folic acid synthesis. a precursor molecule that the body uses to synthesize folic acid in mitochondria.

Curcumin  Studies suggest that curcumin may help enhance mental health and aid in the treatment of conditions like depression and anxiety.  Data compiled from six recent studies and found that curcumin was able to significantly reduce symptoms of both depression and anxiety compared to a placebo with minimal risk of side effects.  Preliminary studies of the effects of curcumin in humans have found that curcumin may improve memory, reduce oxidative damage and enhance cognition.  Derived from turmeric, the curcumin compound is also useful for cognitive enhancement. Increased neurogenesis in the hippocampus region of the brain is thought to cause antidepressant effects in users of this compound as well.

Ginkgo biloba  Research shows that ginkgo can help combat poor concentration, reverse cognitive decline and heal fatigue. It’s also been found to be useful for helping to treat cerebral insufficiency, a condition characterized by chronically low concentration, confusion, decreased physical performance, fatigue, headaches and mood changes. It’s an effective anti-inflammatory that increases antioxidant activity, lowers oxidative stress and improves circulation, all important factors for maintaining cognitive health including improved cognitive function, positive mood, increased energy, improved memory and reduced symptoms related to multiple chronic diseases, including as a natural remedy in ADHD and dementia treatments, and may also aid in symptoms of dyslexia.  For people of all ages, its ability to increase vascular dilation and improve health of blood vessels means it supports brain activity. Multiple studies suggest that ginkgo is a safe and effective way to boost mental capabilities with little risk.

Bacopa monniere   Research suggests Bacopa monniere aids the body’s ability to handle stressors and counteracts the effects of high levels of stress hormones, like cortisol and adrenaline which cause nervousness, depression or mood swings. Known as an adaptogen herb that naturally raises the body’s ability to cope with trouble and worry, it may be especially helpful for people with generalized anxiety disorder (GAD) and possibly seasonal depression, panic attacks and social phobias. The bacosides in Bacopa monnieri sharpens cognitive function by improving transmission of nerve impulses, which makes it a promising for the treatment of ADHD. Bacopa creates a sense of calm and peace, countering the hyperactive and impulsive tendencies of those with ADHD. It also has a unique ability to invigorate mental processes while reducing the effects of stress and nervous anxiety, a powerful combination for an ADHD sufferer’s attention difficulties.

Hericium erinaceus, Possibly the most thoroughly researched feature of this substance derived from what’s commonly known as the lion’s mane mushroom, is its impact on brain cells and related functions. Preliminary research indicates HE may have revolutionary impact on neurodegenerative diseases. One method by which HE affects brain function is by enhancing “neurite outgrowth” in the brain and related organs. Neurite outgrowth refers to the growth of axons and dendrites from neurons. By increasing this growth, it could potentially be possible to slow or reverse cell degeneration in the brain — the main characteristic of diseases like Alzheimer’s and Parkinson’s. A 2012 study found HE could regenerate damaged cells from peripheral nerve injury, an injury affecting the delicate tissue between your brain and spinal cord. Preliminary research also indicates that HE may have a major impact on brain cells, protecting them from damage and delaying their cell death significantly.

Ginseng  has been shown to benefit mental functions, feelings of calmness and mood in both healthy people and those with brain-related disease. Ginseng may help fight fatigue and enhance physical activity by lowering oxidative damage and increasing energy production in cells. Ginseng may improve thinking processes and cognition. Study found that ginseng seems to demonstrate benefits for cognition, behavior, and quality of life. Ginseng has been found to improves mood and reduces stress.  Ginseng demonstrates improvement of brain function. It stimulates brain cells and improves concentration and cognitive activities.

Guarana  The anti-depressive effects of Guarana (aka Paullinia cupana) are actually more potent than many other herbs (performing similarly to the reference drug imipramine) and do not appear to be related to the caffeine content. More recent studies note that guarana was able to enhance cognitive scores related to memory and reaction time. Guaraná has been found to improves the speed of short-term memory, the form of working memory where multiple pieces of information are manipulated simultaneously. Guaraná seed extract improves memory fatigue symptoms of prolonged mental exertion.Guaraná contributes positively to better mood, alertness, and brain activation. Mental fatigue can contribute greatly to frustration, irritability, and bad mood. Research shows that even small doses of guaraná can improve mood.

 

These statements have not been evaluated by the Food and Drug Administration (FDA). This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease.

 

Vitamin D3  Calcitriol, the active form of Vitamin D, is arguably the most powerful hormone in the body. It has the ability to activate over 1,000 genes which is roughly 5% of the human genome. Scientists have linked this nutrient’s activity to a number of functions throughout the body, including the workings of the brain. Research suggests a strong link between vitamin D status and basic cognitive function, mood and overall mental health.

Higher Vitamin E intake is associated with healthy cognitive function. Vitamin E provides protection against free radicals, molecules that can damage cells, including brain cells, tissues and organs. Free radicals form as a result of normal body processes. They cause damage that shortens the life of your cells. Vitamin E is a powerful antioxidant that may help reduce free radical damage and slow the aging process of your cells, according to the National Institutes of Health (NIH).

Vitamin C is among the best vitamins for the brain. It aids in multiple functions in the brain. Improved Circulation: By helping to build collagen that keeps arteries flexible, vitamin C improves blood flow.  Increased blood flow delivers more oxygen and nutrients to your brain, keeping it properly nourished, enabling proper cognition and other brain functions.

B-Complex Vitamins When you think of the “B” in B Complex Vitamins , think B, for Brain. Imbalances of the major brain chemicals can significantly alter your mental health. The B-Complex Vitamins play an essential role in modulating brain chemicals.  An important role of B vitamins for brain health is the production of the neurotransmitters serotonin, dopamine and GABA.  Boosting your B vitamins intake can improve your neurotransmitter balance and your mental well-being. A serotonin deficiency can contribute to anxiety, insomnia, low self-esteem, negative thoughts, OCD and SAD (seasonal affective disorder). Without adequate GABA (gamma-aminobutyric acid), persons can be easily stressed, overstimulated and overwhelmed. Dopamine helps focus and concentration. Symptoms of a low dopamine level are low energy and motivation. B vitamins can improve energy levels and increase your tolerance to stress. B Vitamins with Folic Acid prevents mental decline. B6, B12 and folic acid (B9) are especially vital for brain health. Studies have shown that these vitamins work together to help prevent mental decline, dementia and Alzheimer’s disease.

A Special Note: A Very Common Deficiency: Vitamin B12. This is a very prevalent vitamin deficiency in the US. Vitamin B12 deficiency is a serious matter and should not be taken lightly. It can lead to a wide spectrum of mental disorders including memory loss, dementia, depression, and even measurable brain atrophy.

Folic Acid  Folates are important in the nervous system at all ages and there is growing evidence of their involvement in the ageing brain, especially in mood and cognitive function. Folates supports neurotransmitter synthesis — which in turn helps maintain cognitive abilities. Open and controlled treatment studies confirm an aetiological link with specific effects of the vitamin on mood, drive, initiative, alertness, concentration, psychomotor speed, and social activity. These observations are reinforced by the cognitive studies in otherwise healthy subjects, suggesting that low folate levels are associated with patterns of impairment.

Zinc is an essential mineral that plays a vital role in brain health. A zinc deficiency may have an effect on other nutrients that help the brain function. The Mayo Clinic reports that zinc supplements may benefit symptoms of hyperactivity, impulsivity, and social problems. Regarding brain-related cognition an improvement in cognition has been seen in stroke patients given zinc to complement their zinc insufficient diet. Zinc has been previously associated with an improvement in mood state and has mechanisms by which it can work Secondary to an improvement in overall mood, aggressive symptoms have been noted to be reduced with low dose zinc supplementation. Zinc deficiency is something that’s very common and can cause a number of health issues. It is estimated that about 75 percent of people  today are deficient in zinc and/or show display zinc deficiency symptoms. The top 2 causes of Zinc deficiency are 1. Stress. High levels of emotional stress can deplete zinc and zinc is a reparative mineral that the body needs to heal and repair the body, brain, skin and organs. 2. Overtraining: The second most common cause of zinc deficiency is over-exercise and overtraining. Triathletes, marathon runners and CrossFit athletes and persons engaged in high-intensity training (HITT) are some of the people that are most susceptible to a zinc deficiency.

Magnesium deficiency is one of the leading nutrient deficiencies in adults with an estimated 80 percent being deficient in this vital mineral. Magnesium is an essential dietary mineral, and the second most prevalent electrolyte in the human body.  A deficiency causes neural excitation, increases blood pressure and reduces glucose tolerance. Magnesium is vital for GABA function, an inhibitory neurotransmitter that produces serotonin. Certain hormones, including serotonin, regulated by magnesium are crucial for calming the brain and promoting relaxation, which is one reason why a magnesium deficiency can lead to sleeplessness or insomnia. Maintaining healthy magnesium levels is also associated with a protective effect against depression and ADHD. Initial scientific research into the effects of magnesium supplementation boosting physical performance is promising. Magnesium plays a critical role in brain function and mood, and low levels are linked to an increased risk of depression.

Selenium is an extremely important micronutrient that may be low in the diets of some modern populations, leading to chronic health problems. Selenium is key to one of the body’s primary antioxidants, glutathione peroxidase. This complex keeps the delicate polyunsaturated acids in cell membranes from getting oxidized (rancid). Proper amounts of glutathione peroxidase are necessary to protect cell membranes. A recent University of Otago study published in the prestigious Journal of Nutrition has found that selenium levels that are both too high in the body, and far worse, too low, can place young people at greater risk of depression, lower concentrations of selenium were found to be even more detrimental to these outcomes. Oxidative stress is believed to be involved in both the onset and the progression of neurological diseases like Parkinson’s, multiple sclerosis and Alzheimer’s disease. Several studies have shown that patients with Alzheimer’s disease have lower blood levels of selenium.  Additionally, some studies have shown that selenium in both food and supplements may improve memory in patients with Alzheimer’s disease.

MAX-BRAIN-16 Brain Power Blend, formulated by Pharma Natural’s Natural Health Sciences Research & Development Laboratory is a proprietary blend of natural substances, each having been found to aid brain functions and support healthy brain cells, including:

Phosphatidylcholine offers many different benefits for your brain. This nootropic compound is used to boost memory, enhance intellectual skills, increase concentration, and improve overall brain health. Phosphatidylcholine benefits are derived from the fact that it is a source of choline which is an essential nutrient necessary for proper brain function.  A large part of the volume of brain cells are comprised of Choline (in various forms) and it is incorporated in all neuron cell membranes.

Phosphatidylinositol is present in all tissues and cell types, especially brain tissue. Derivatives of this phospholipid serve as messenger molecules with the nervous system. Phosphatidylinositol is an important lipid, both as a key membrane constituent and as a participant in essential metabolic processes, both directly and via a number of metabolites. Phosphatidylinositol is especially abundant in brain tissue, where it can amount to 10% of the phospholipids. Phosphatidylinositol is involved in the phosphoinositide signal transduction system, one of the primary means for intercellular communication in the central nervous system. Investigators have begun to examine the effects of neurological and psychiatric diseases on the activity of the phosphoinositide system. Alzheimer’s disease has been studied to the greatest extent and a severe deficit in phosphoinositide signaling has been identified in most studies.

 

GABA is the most potent depressive neuroamine in human brains. It regulates many of the sedative actions in brain tissue and is critical for relaxation. GABA regulates unwanted firing of neurons not only in the brain, but in nerve connections to muscles and glands as well, in addition to improving sleep, it can also be useful in a wide array of situations including: calming nerves, improving mood and reducing anxiety.

Carnosine is a peptide the body uses to repair tissues and clear away toxins. It increases the energy output of cellular mitochondria.  Emerging research indicates that Carnosine can revive mitochondria. It can even rescue brain cells if their mitochondria have stopped functioning. Carnosine can reverse mitochondrial failure. Brain tissue naturally contains high levels of carnosine, which can reduce the oxidative, nitrosative, and glycemic stress to which the brain is especially vulnerable. Oxidation and glycation produce inflammation. Carnosine can preserve normal neuronal function, and helps minimize toxicity created by the high levels of metal ions that are present in certain areas of the brain.

Tyrosine benefits mental health in many ways. It’s a precursor to major neurotransmitters and can help with dopamine-related depression, ADHD, and extreme stress. Tyrosine is a naturally occurring compound of primary importance for mental health. It is a precursor to some of the most important brain chemicals and hormones. Tyrosine is an amino acid involved in the structure of almost every protein in the body. Tyrosine is one of the handful of conditional amino acids.  means that your body can usually make what it needs, but not always in adequate amounts. Stress, overwork, lack of sleep, illness, or eating too little protein can all increase your need for tyrosine. Tyrosine is a precursor to three important neurotransmitters: dopamine, epinephrine and norepinephrine. Neurotransmitters are chemicals that brain cells use to communicate with each other. They have profound effects on every aspect of your life.

Astaxanthin is primarily known for its immune boosting and anti-inflammatory properties. There is ample evidence that astaxanthin can reduce inflammation This is primarily due to anti-oxidant properties, which are said to promote the longevity of cells as well. Some studies suggest that these anti-inflammatory properties reduce cognitive deficits . Recent studies also show that astaxanthin can help to reduce signs of aging by increasing brain-derived neurotrophic factor (BDNF) and combating oxidative stress in the brain  BDNF are associated with neurogenesis and growth.

Carnitine, (as Acetyl l-carnitine), is an amino acid that helps the body produce energy. It is also a powerful antioxidant and crosses the blood-brain barrier where it both plays a role in the production of the neurotransmitter acetylcholine and supports healthy blood flow to the brain. Acetylcholine is integral to healthy memory, learning, computation, analysis, perception, and many other cognitive functions. Higher levels of acetylcholine may result in greater synaptic flexibility and memory formation, two indicators of healthy brain function. ALCAR is an excellent brain booster and natural antidepressant that works by increasing levels of both norepinephrine and serotonin. Norepinephrine deficiency is linked to a substantial number of mental health disorders.

Glutamic Acid, glutamine is one of 20 naturally occurring amino acids in dietary protein. In fact, L-glutamine is the most abundant amino acid in the bloodstream and makes up 30–35 percent of the amino acid nitrogen in your blood. It’s known as a conditionally essential amino acid because your body uses it in large amounts.  A precursor to the neurotransmitter glutamate in your brain, glutamine is key to boosting your brain health. Disruption of the glutamine-glutamate cycle can result in a number of brain problems, including Reye’s Syndrome, epilepsy, bipolar disorder, schizophrenia, anxiety, depression and alcohol addiction. Glutamine also provides brain-related anti-aging properties. Mitochondrial dysfunction causes abnormal increases in the neurotransmitter glutamate, putting the brain at risk.

PABA, para-aminobenzoic acid (or PABA) encourages folic acid synthesis. a precursor molecule that the body uses to synthesize folic acid in mitochondria.

Curcumin  Studies suggest that curcumin may help enhance mental health and aid in the treatment of conditions like depression and anxiety.  Data compiled from six recent studies and found that curcumin was able to significantly reduce symptoms of both depression and anxiety compared to a placebo with minimal risk of side effects.  Preliminary studies of the effects of curcumin in humans have found that curcumin may improve memory, reduce oxidative damage and enhance cognition.  Derived from turmeric, the curcumin compound is also useful for cognitive enhancement. Increased neurogenesis in the hippocampus region of the brain is thought to cause antidepressant effects in users of this compound as well.

Ginkgo biloba  Research shows that ginkgo can help combat poor concentration, reverse cognitive decline and heal fatigue. It’s also been found to be useful for helping to treat cerebral insufficiency, a condition characterized by chronically low concentration, confusion, decreased physical performance, fatigue, headaches and mood changes. It’s an effective anti-inflammatory that increases antioxidant activity, lowers oxidative stress and improves circulation, all important factors for maintaining cognitive health including improved cognitive function, positive mood, increased energy, improved memory and reduced symptoms related to multiple chronic diseases, including as a natural remedy in ADHD and dementia treatments, and may also aid in symptoms of dyslexia.  For people of all ages, its ability to increase vascular dilation and improve health of blood vessels means it supports brain activity. Multiple studies suggest that ginkgo is a safe and effective way to boost mental capabilities with little risk.

Bacopa monniere   Research suggests Bacopa monniere aids the body’s ability to handle stressors and counteracts the effects of high levels of stress hormones, like cortisol and adrenaline which cause nervousness, depression or mood swings. Known as an adaptogen herb that naturally raises the body’s ability to cope with trouble and worry, it may be especially helpful for people with generalized anxiety disorder (GAD) and possibly seasonal depression, panic attacks and social phobias. The bacosides in Bacopa monnieri sharpens cognitive function by improving transmission of nerve impulses, which makes it a promising for the treatment of ADHD. Bacopa creates a sense of calm and peace, countering the hyperactive and impulsive tendencies of those with ADHD. It also has a unique ability to invigorate mental processes while reducing the effects of stress and nervous anxiety, a powerful combination for an ADHD sufferer’s attention difficulties.

Hericium erinaceus, Possibly the most thoroughly researched feature of this substance derived from what’s commonly known as the lion’s mane mushroom, is its impact on brain cells and related functions. Preliminary research indicates HE may have revolutionary impact on neurodegenerative diseases. One method by which HE affects brain function is by enhancing “neurite outgrowth” in the brain and related organs. Neurite outgrowth refers to the growth of axons and dendrites from neurons. By increasing this growth, it could potentially be possible to slow or reverse cell degeneration in the brain — the main characteristic of diseases like Alzheimer’s and Parkinson’s. A 2012 study found HE could regenerate damaged cells from peripheral nerve injury, an injury affecting the delicate tissue between your brain and spinal cord. Preliminary research also indicates that HE may have a major impact on brain cells, protecting them from damage and delaying their cell death significantly.

Ginseng  has been shown to benefit mental functions, feelings of calmness and mood in both healthy people and those with brain-related disease. Ginseng may help fight fatigue and enhance physical activity by lowering oxidative damage and increasing energy production in cells. Ginseng may improve thinking processes and cognition. Study found that ginseng seems to demonstrate benefits for cognition, behavior, and quality of life. Ginseng has been found to improves mood and reduces stress.  Ginseng demonstrates improvement of brain function. It stimulates brain cells and improves concentration and cognitive activities.

Guarana  The anti-depressive effects of Guarana (aka Paullinia cupana) are actually more potent than many other herbs (performing similarly to the reference drug imipramine) and do not appear to be related to the caffeine content. More recent studies note that guarana was able to enhance cognitive scores related to memory and reaction time. Guaraná has been found to improves the speed of short-term memory, the form of working memory where multiple pieces of information are manipulated simultaneously. Guaraná seed extract improves memory fatigue symptoms of prolonged mental exertion.Guaraná contributes positively to better mood, alertness, and brain activation. Mental fatigue can contribute greatly to frustration, irritability, and bad mood. Research shows that even small doses of guaraná can improve mood.

 

Vitamin D3 (as cholecalciferol)

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Vitamin+D3

https://www.vitamindcouncil.org/vitamin-d-pharmacology/

  1. Barker JN, Ashton RE, Marks R, Harris RI, Berth-Jones J. Topical maxacalcitol for the treatment of psoriasis vulgaris: a placebo-controlled, double-blind, dose-finding study with active comparator. Br J Dermatol. 1999.
  2. Fukuoka M, Sakurai K, Ohta T, Kiyoki M, Katayama I. Tacalcitol, an active vitamin D3, induces nerve growth factor production in human epidermal keratinocytes. Skin Pharmacol Appl Skin Physiol. 2001
  3. Kragbelle, K. Treatment of psoriasis with calcipotriol and other Vitamin D analogues. J. Am. Acad. Dermatol., 1992.
  4. Kubodera, N and Takahashi F. “Analogs for the Treatment of Osteoporosis.” In Vitamin D, Third Edition, by Feldman D, Pike JW and Adams JS, 995-1018. Elsevier Academic Press, 2011.
  5. Morii H. Falecalcitriol as a new therapeutic agent for secondary hyperparathyroidism. Clin Calcium. 2005.
  6. Vieth, R. “The Pharmacology of Vitamin D, Including Fortification Strategies.” In Vitamin D, Second Edition, by Feldman D, Pike JW and Gloreieux FH, 995-1018. Elsevier Academic Press, 2005.

https://www.vitamindcouncil.org/health-conditions/cognitive-impairment/

Vitamin D and Neurocognitive Dysfunction: Preventing “D”ecline?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829975/

The Effects of Vitamin D3 on Brain Development:

https://www.tandfonline.com/doi/abs/10.5455/bcp.20141024012912#aHR0cHM6Ly93d3cudGFuZGZvbmxpbmUuY29tL2RvaS9wZGYvMTAuNTQ1NS9iY3AuMjAxNDEwMjQwMTI5MTI/bmVlZEFjY2Vzcz10cnVlQEBAMA

Sato Y, et al. Amelioration of osteopenia and hypovitaminosis D by 1alpha-hydroxyvitamin D3 in elderly patients with Parkinson’s diseaseJ Neurol Neurosurg Psychiatry. (1999)

Grant WB, Holick MF. Benefits and requirements of vitamin D for optimal health: a reviewAltern Med Rev. (2005)

Trang HM, et al. Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2Am J Clin Nutr. (1998)

Capiati D, Benassati S, Boland RL. 1,25(OH)2-vitamin D3 induces translocation of the vitamin D receptor (VDR) to the plasma membrane in skeletal muscle cellsJ Cell Biochem. (2002)

Vitamin E

https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/

https://www.ncbi.nlm.nih.gov/pubmed/16011463

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Vitamin+E&_ga=2.133824521.624309031.1531247253-993174575.1530910425

Morrison D, et al. Vitamin C and E supplementation prevents some of the cellular adaptations to endurance-training in humansFree Radic Biol Med. (2015)

Vitamin C

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Vitamin+C

Harrison FE1, May JM. Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2Free Radic Biol Med. (2009)

Padayatty SJ1, et al. Vitamin C as an antioxidant: evaluation of its role in disease preventionJ Am Coll Nutr. (2003)

Agus DB, et al. Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transportersJ Clin Invest. (1997)

Brody S. High-dose ascorbic acid increases intercourse frequency and improves mood: a randomized controlled clinical trialBiol Psychiatry. (2002)

B-Complex Vitamins

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=B-Complex+

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/

https://www.ars.usda.gov/news-events/news/research-news/2010/b-vitamins-and-the-aging-brain-examined/

https://www.ncbi.nlm.nih.gov/pubmed/15671130

Folic Acid

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=folic+acid

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1123448/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC318492/

https://ods.od.nih.gov/factsheets/Folate-Consumer/

Zinc

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=zinc

Normalization Of Zinc Intake Enhances Neurological Retrieval Of Patients Suffering From Ischemic Strokes

Effect of Zinc Supplementation On Mood States In Young Women: A Pilot Study

https://ods.od.nih.gov/factsheets/Zinc-Consumer/

Magnesium

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-

https://www.ncbi.nlm.nih.gov/pubmed/23950577

https://www.ncbi.nlm.nih.gov/pubmed/25748766

https://www.ncbi.nlm.nih.gov/pubmed/16542786

https://www.ncbi.nlm.nih.gov/pubmed/25748766

https://www.ncbi.nlm.nih.gov/pubmed/16542786

https://www.ncbi.nlm.nih.gov/pubmed/19271419

https://www.ncbi.nlm.nih.gov/pubmed/19271419

https://www.naturalfoodseries.com/15-benefits-magnesium/#8_Helps_Treat_Psychiatric_Dysfunctions

Selenium

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=selenium

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147716/

https://www.ncbi.nlm.nih.gov/pubmed/24668390

http://www.sciencedirect.com/science/article/pii/S2352873717300409

https://www.ncbi.nlm.nih.gov/pubmed/21775560

Phosphatidylcholine

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Phosphatidylcholine

https://www.medicinenet.com/phosphatidylcholine/supplements-vitamins.htm

https://www.healthline.com/health/food-nutrition/phosphatidylcholine

https://nootriment.com/phosphatidylcholine-benefits/

Phosphatidylinositol

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Phosphatidylinositol

https://www.ncbi.nlm.nih.gov/pubmed/8971982#

http://www.lipidhome.co.uk/lipids/complex/pi/index.htm

GABA

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Gamma-aminobutyric+acid

https://draxe.com/gaba/

https://examine.com/supplements/gaba/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594160/

Carnosine

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Carnosine

https://www.organicfacts.net/carnosine.html

https://www.webmd.com/vitamins/ai/ingredientmono-1038/carnosine

Tyrosine

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Tyrosine

https://www.verywellfit.com/the-benefits-of-tyrosine-89523

https://www.healthline.com/nutrition/tyrosine

Astaxanthin

https://www.healthline.com/health/health-claims-astaxanthin

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Astaxanthin

https://draxe.com/astaxanthin-benefits/

Carnitine

https://www.ncbi.nlm.nih.gov/pubmed/2387659

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Carnitine

https://www.healthydirections.com/acetyl-l-carnitine-top-supplement-for-promoting-brain-function

Glutamic Acid

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Glutamic+Acid

https://draxe.com/l-glutamine-benefits-side-effects-dosage/

https://www.naturalpedia.com/glutamic-sources-health-benefits-and-uses.html

PABA

https://www.naturalpedia.com/paba-sources-health-benefits-and-uses.html

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=+para-aminobenzoic+acid

Curcumin

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Curcumin

https://www.nootropedia.com/curcumin/

https://www.ncbi.nlm.nih.gov/pubmed/23146777

https://examine.com/supplements/curcumin/

https://draxe.com/curcumin/

Ginko Biloba

https://www.naturalfoodseries.com/7-benefits-ginkgo-biloba/

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=Ginko+Biloba

https://draxe.com/ginkgo-biloba-benefits/

Bacopa Monniere

https://www.ncbi.nlm.nih.gov/pubmed/23772955

https://examine.com/supplements/bacopa-monnieri/

Hericium Erinaceus

https://draxe.com/lions-mane-mushroom/

http://www.greenmedinfo.com/blog/lion-s-mane-mushroom-unparalleled-benefits-your-brain-and-nervous-system

Ginseng

https://www.healthline.com/nutrition/ginseng-benefits#section2

https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v%3Aproject=medlineplus&v%3Asources=medlineplus-bundle&query=ginseng

https://draxe.com/ginseng-benefits/

https://examine.com/supplements/panax-ginseng/#citations

Gurarana

https://universityhealthnews.com/daily/memory/exotic-brain-enhancer-guarana-seed-extract-improves-memory-and-focus/

https://examine.com/supplements/paullinia-cupana/