Enlargement of the prostate or benign prostatic hyperplasia (BPH), is common in men older than 50 years old. Additionally, in both young and aged men, prostatic diseases or an unhealthy prostate can affect spermatozoa functioning and, therefore, male fertility. BPH occurs when the cells of the prostate gland begin to multiply. The additional cells cause the prostate gland to swell, which in turn, restricts the urethra and limit the flow of urine. BPH is not prostate cancer, nor does it increase the risk of cancer. Although, BPH causes symptoms that can affect your quality of life.
Saw Palmetto (Serenoa repens)
Consideration of prostate physiology emphasizes a number of points including the influence of bacteria-related prostatic inflammation on male fertility; and the potential role of prostatic inflammation in promoting the development of BPH and carcinogenesis.
In a randomized, double-blind, placebo-controlled trial of saw palmetto in men with lower urinary tract symptoms, Saw palmetto led to a statistically significant improvement in urinary symptoms in men with lower urinary tract symptoms compared with placebo.
A hexanic lipidosterolic extract of saw palmetto (Serenoa repens) has shown properties that highlight its benefit in the management of benign prostate hyperplasia (BPH). To address its actual anti-inflammatory potency a study was conducted which indicated that the hexanic lipidosterolic extract of saw palmetto exerted potent anti-inflammatory properties in the whole prostate supporting the beneficial role of the lipidosterolic extract of saw palmetto for BPH.
Some research suggests that saw palmetto phytosterols, including β-Silosterol, inhibit 5α-reductase, BPH symptoms. The bioactive components of saw palmetto are fatty acids and phytosterols. Saw palmetto extracts predominantly consist of fatty acids (~90%) and are unique compared with other extracts and vegetable and nut oils  in that they are a rich source of the saturated, medium-chain fatty acids laurate (12:0) and myristate (14:0) .
Several studies suggest that the fatty acids in saw palmetto extracts are responsible for its ability to inhibit 5α-reductase [21,22,23,24,25,26], but which fatty acid(s) is/are responsible for the inhibition varies. Some research suggests that saw palmetto phytosterols (β-Silosterol, campesterol, stigmasterol), inhibit 5α-reductase, prostate cancer cell/tumor growth, and/or BPH symptoms [27,28,29,30,31]. A combination of fatty acids, phytosterols, and other bioactive components may be responsible for beneficial effects reported from saw palmetto supplements.
African Prune (P. africanum) is an herbal extract taken from the bark of the African cherry tree. The tree is also known as the African plum tree, or Prunus africanum. Initial research showed that African Prune was effective at symptom relief. More recent research suggests that the extract may help the condition itself. The evidence suggests that P. africanum modestly, but significantly, improves urologic symptoms and flow measures.
A 2012 study suggested that P. africanum may help slow the growth of actual prostate cells, possibly inhibiting BPH development. P. africanum remains amongst one of the most research-supported herbal remedies for BPH.
Zinc, like many other nutrients, is not produced naturally by the body because of this it must be obtained from supplements or food. This essential nutrient is required in numerous processes including immune function, gene expression, DNA and protein synthesis, and more. Zinc’s role in immune function is one reason why it is included in nasal spray, lozenges, and other natural cold treatments. Studies have shown that zinc supplements help keep the immune system strong. A metaanalysis on the efficacy of zinc found that 80 to 92 milligrams per day of reduced the duration of the common cold by 33%. Additionally, it’s been shown that older adults taking zinc supplements significantly reduced the risk of infectious diseases and improve immune response. One of zincs important roles is the decrease of oxidative stress and reduction of certain inflammatory proteins. Oxidative stress is a physiological stress on the body that is caused by cumulative damage done by free radicals that were not destroyed by antioxidants. Oxidative stress leads to chronic inflammation which leads to various chronic illnesses. https://ods.od.nih.gov/factsheets/%20Zinc-HealthProfessional/, https://www.ncbi.nlm.nih.gov/pubmed/28515951, https://www.ncbi.nlm.nih.gov/books/NBK493173/
A 23-year study of more than 46,000 men considered the link between lycopene and prostate-centric diseases. The Study found that men who consumed at least two servings of lycopene-rich tomato sauce per week were 30% less likely to develop a prostate disease than those who ate less than one serving of tomato sauce per month.
Additionally, a recent review of 26 studies found high lycopene intakes to a 9% lower likelihood of developing prostate disease. Daily intakes of 9–21 mg per day appeared most beneficial.
Deficiency or excess of certain trace elements has been considered as risk factor for prostate cancer. This study was aimed to detect differential changes and mutual correlations of selected trace elements in prostate cancer tissue versus benign prostatic hyperplasia tissue. Zinc, copper, iron, calcium and selenium were analyzed. The malignant prostatic tissue has significantly lower zinc and selenium level, a lower Zn/Fe ratio and a positive direct correlation of Se with Zn and Fe as compared to benign prostatic hyperplasia tissue.
These statements have not been evaluated by the Food and Drug Administration (FDA). This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease.