Glucosamine is a natural amino sugar produced by your body. The highest natural concentration of glucosamine is in joints and cartilage where it makes up the structure of compounds essential for joint health. There are two main types of glucosamine supplements: glucosamine sulfate and glucosamine. Several studies suggest that taking glucosamine supplements may reduce collagen breakdown. https://www.ncbi.nlm.nih.gov/pubmed/23358550 https://www.ncbi.nlm.nih.gov/pubmed/19724889
Glucosamine supplements may work by reducing inflammation, which is one of the main causes of joint cartilage breakdown in osteoarthritis patients. https://www.ncbi.nlm.nih.gov/pubmed/17257091
Due to the research in the last 5 years that the scientific basis underlying its beneficial effects are starting to be clarified. In randomized, double-blind, placebo-controlled trials, this compound clinically controls pain and produces beneficial effects in patients with knee osteoarthritis, possibly delaying the appearance of long-term structural changes in the joint (i.e., it has a structure-modifying effect). https://www.ncbi.nlm.nih.gov/pubmed/17257091
Chondroitin is a component of human connective tissues found in cartilage and bone. Laboratory studies have found that chondroitin can reduce the activity of enzymes and substances that break down collagen in joints. Glucosamine and chondroitin sulfate, alone or in combination, are used worldwide by individuals suffering from osteoarthritis pain. Newer studies have provided a better perspective on the potential benefits that they can offer. Because the 2 in combination showed a significant level of efficacy in the moderate-to-severe knee osteoarthritis. https://www.versusarthritis.org/about-arthritis/complementary-and-alternative-treatments/types-of-complementary-treatments/chondroitin/
Preclinical studies show that Hydrolyzed Collagen (hc) stimulates collagenic tissue regeneration by increasing not only collagen synthesis but minor components (glycosaminoglycan and hyaluronic acid) synthesis as well. Clinical studies show that continual consumption of hc helps to reduce and prevent joint pain, bone density loss and skin ageing. These results as well as its high level of tolerance and safety make hc supplementation viable for a long-term use in bone and joint degenerative diseases and in fight against skin ageing. https://www.ncbi.nlm.nih.gov/pubmed/26267777
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This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure or prevent any disease.