Scientific research suggests that L-Carnitine may contribute to increased endurance, lessen muscle damage, improve fat utilization, possibly aid in weight loss and enhanced brain function in elderly persons. Carnitine is a type of amino acid that benefits energy levels by transporting fatty acids into the mitochondria to be used as fuel. Two human studies have confirmed the beneficial effects of this amino acid on endurance levels. In one study published in the Journal of Strength and Conditioning Research, giving professional soccer players three to four grams of L-carnitine before exercise was found to prolong the time it took to reach exhaustion. https://www.ncbi.nlm.nih.gov/pubmed/24263659
Besides increasing endurance this amino acid also aids in preventing and protecting against muscle damage. In one 2014 study published in the Asian Journal of Sports Medicine, 21 male athletes were given either L-carnitine or a placebo daily for two weeks prior to an athletic test. Compared to the control group, those who took L-carnitine were found to have lower levels of certain markers that indicate muscle damage. https://www.ncbi.nlm.nih.gov/pubmed/25834706
While the evidence of L-Carnitine contributing to improved fat utilization and aid in weight loss is not considered conclusive, in a study providing a systematic review and meta-analysis of randomized controlled trials, which have examined the effect of the carnitine on adult weight loss, results from meta-analysis of eligible trials revealed that subjects who received carnitine lost significantly more weight and showed a decrease in body mass index compared with the control group. https://www.ncbi.nlm.nih.gov/pubmed/27335245
A study of elderly persons indicated that carnitine produced a reduction of total fat mass, increased total muscular mass, and facilitates an increased capacity for physical and cognitive activity by reducing fatigue and improving cognitive functions. https://www.ncbi.nlm.nih.gov/pubmed/18065594
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