Health Bulletin #4
from Pharma Natural’s Natural Health Sciences Research & Development Laboratory

A Robust Immune System


What We Can Do to Support our Immune System while a COVID-19 Vaccine and Treatment Medicines are Developed

Nutrition is a critical determinant of immune responses and malnutrition is the most common cause of immunodeficiency worldwide. Deficiency of single nutrients also results in altered immune responses: this is observed even when the deficiency state is relatively mild. Of the micronutrients, zinc; selenium; iron; copper; vitamins A, C, E, and B-6; and folic acid have important influences on immune responses.

Published Research and Articles on Vitamin C as a Consideration for Pneumonia, Lung Infections, and the Novel Coronavirus (SARS-CoV-2/COVID-19)

Vitamin C supports your immune system. Vitamin C helps to kill viruses and reduces the symptoms of infection. It’s not a COVID-19 “cure,” but nothing is. Nothing is proven to work against COVID-19, because it is a new virus. Vitamin C has worked against every single virus including influenzas, pneumonia, and even poliomyelitis. In the medical literature, there are more than 64,000 published articles and studies on Vitamin C available at The U.S. National Library of Medicine National Center for Biotechnology Information [1]. Vitamin C is arguably one of the most researched substances in existence.
Vitamin D supplementation reduces the risk of respiratory infection, regulates cytokine production and can limit the risk of other viruses such as influenza. A respiratory infection can result in cytokine storms – a vicious cycle in which our inflammatory cells damage organs throughout the body –
Adequate intakes of vitamins and trace elements are required for the immune system to function efficiently. Micronutrient deficiency suppresses immune functions by affecting the innate T-cell-mediated immune response and adaptive antibody response, and leads to dysregulation of the balanced host response. This increases the susceptibility to infections, with increased morbidity and mortality. In turn, infections aggravate micronutrient deficiencies by reducing nutrient intake, increasing losses, and interfering with utilization by altering metabolic pathways.  Antioxidant vitamins and trace elements (vitamins C, E, selenium, copper, and zinc) counteract potential damage caused by reactive oxygen species to cellular tissues and modulate immune cell function  Adequate intake of vitamins B(6), folate, B(12), C, E, and of selenium, zinc, copper, and iron supports immune response with sufficient production of proinflammatory cytokines, which maintains an effective immune response and avoids a shift to an anti-inflammatory cell-mediated immune response and an increased risk of extracellular infections. Supplementation with these micronutrients reverses mediated immune response to a proinflammatory with enhanced innate immunity. Vitamins A and D play important roles in both cell-mediated and humoral antibody response and support an anti-inflammatory profile.

Pharma Natural Natural Health Sciences

Pharma Natural Health Sciences is dedicated to the improvement of human health based on scientific research through the application of such research in the nutriceutical products we manufacture. Our Health Sciences team employs a multi-disciplinary approach of applied natural sciences, engineering and technology to our domain, Nutrition, which is the science that interprets the interaction of nutrients and other substances in food in relation to maintenance, growth, reproduction, health and disease in human beings. It includes absorption, assimilation, catabolism, biosynthesis, and excretion.


Nutriceutical Product Integrity

The immune system is a complex system of specialized cells and biological responses integrated into the entire body, from digestion to brain chemistry and everywhere else in the body. There is a large body of proven research about how certain vitamins and minerals may support the immune system. The vitamins A, B6, B12, C, D, E and folic acid and the trace elements iron, zinc, copper and selenium work in synergy to support the protective activities of the immune cells. All these micronutrients, with the exception of vitamin C and iron, are essential for antibody production. Overall, inadequate intake and status of these vitamins and trace elements may lead to suppressed immunity, which predisposes to infections and aggravates malnutrition. Therefore, supplementation with these selected micronutrients can support the body’s natural defense system by enhancing all three levels of immunity.

Vitamin C is an essential micronutrient for humans.  Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C deficiency results in impaired immunity and higher susceptibility to infections. It is a potent antioxidant and a cofactor for a family of biosynthetic and gene regulatory enzymes. Infections significantly impact on vitamin C levels due to enhanced inflammation and metabolic requirements. Furthermore, supplementation with vitamin C appears to be able to both prevent and treat respiratory and systemic infections.

Vitamin D is involved in immune function, disease prevention and is vital to several different aspects of health. Although it’s most well-known for its ability to strengthen the bones and boost calcium absorption, it alsoaffects mood regulation and weight control. A deficiency in this crucial vitamin can cause issues like hair loss, chronic pain, sluggishness and decreased wound healing. Research suggests the vitamin D may have numerous benefits related to cancer, muscle strength, and mental health.

Zincan essential nutrient, is required in numerous processes including immune function, gene expression, DNA and protein synthesis, and more. Zinc’s role in immune function is one reason why it is a popular natural cold treatment. Studies have shown that zinc supplements help keep the immune system strong. A metanalysis on the efficacy of zinc found that 80 to 92 milligrams per day of reduced the duration of the common cold by 33%. Additionally, it’s been shown that older adults taking zinc supplements significantly reduced the risk of infectious diseases and improve immune response. Zinc like many other nutrients, is not produced naturally by the body because of this it must be obtained from supplements or food.

Echinacea is best known for its positive effects on the immune system. Numerous studies have shown that this herb supports immune system function, reducing the risk of contracting viruses and infections. One study done reported that the immune system benefited from 10 milligrams of echinacea per one kilogram of body weight, taken every day over a 10-day period. A meta-analysis found that echinacea may decrease the risk of catching the common cold by more than 50% and reduce the duration by one and a half days. Echinacea is a popular herb used worldwide. These plants contain a variety of active compounds that function as antioxidants used to defend cells against oxidative stress, a state linked to various diseases.

Probiotics  70-80% of our entire immune system resides within the digestive system. When necessary, inflammation in the intestines creates a pathway for the immune system to carry out an attack against invading viruses and bacteria. However, when inflammation is present but not needed, illnesses such as chronic infections can occur. Probiotics can also modulate the immune system, enhancing the body’s innate immunity. This modulating effect helps alleviate excessive inflammation in the digestive system, thereby boosting immune function.  Probiotics offer a beneficial defense against the effects caused by this unwarranted inflammation. Probiotics help keep the digestive system healthy, to ensure the immune system functions well. Epithelial tissues in the intestines form a barrier against pathogenic microbes and other harmful substances present. Probiotics foster intestinal epithelial cell survival, strengthen cell barrier function, and initiate protective responses

Immune C Liquid form for Children & Elderly Strong Antioxidant, Supports Healthy Immune System. Vitamin C is an antioxidant that helps support the immune system and helps neutralize free radicals in the body. Supplementation with vitamin C appears to be able to both aid in the prevention and treatment of respiratory and systemic infections. Vitamin C is an essential micronutrient for humans.  It is a potent antioxidant and a cofactor for a family of biosynthetic and gene regulatory enzymes. Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C deficiency results in impaired immunity and higher susceptibility to infections. In turn, infections significantly impact on vitamin C levels due to enhanced inflammation and metabolic requirements.

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