Health Bulletin #3
from Pharma Natural’s Natural Health Sciences Research & Development Laboratory
THE NEXT 30 DAYS
2 Keys to Defeating COVID-19
1. Social Distancing
2. Nutritionally Fortifying Our Immune System
Intended impact of social distancing measures as nonpharmaceutical interventions for an influenza pandemic.
Adapted from similar diagrams in the European Centre for Disease Prevention and Control Technical Report and the Centers for Disease Control and Prevention Guidance Report.
What We Can Do to Support our Immune System while a COVID-19 Vaccine and Treatment Medicines are Developed
Nutrition is a critical determinant of immune responses and malnutrition is the most common cause of immunodeficiency worldwide. Deficiency of single nutrients also results in altered immune responses: this is observed even when the deficiency state is relatively mild. Of the micronutrients, zinc; selenium; iron; copper; vitamins A, C, E, and B-6; and folic acid have important influences on immune responses.
Pharma Natural Natural Health Sciences
Pharma Natural Health Sciences is dedicated to the improvement of human health based on scientific research through the application of such research in the nutriceutical products we manufacture. Our Health Sciences team employs a multi-disciplinary approach of applied natural sciences, engineering and technology to our domain, Nutrition, which is the science that interprets the interaction of nutrients and other substances in food in relation to maintenance, growth, reproduction, health and disease in human beings. It includes absorption, assimilation, catabolism, biosynthesis, and excretion.
Nutriceutical Product Integrity
Adequate intakes of vitamins and trace elements are required for the immune system to function efficiently. Micronutrient deficiency suppresses immune functions by affecting the innate T-cell-mediated immune response and adaptive antibody response, and leads to dysregulation of the balanced host response. This increases the susceptibility to infections, with increased morbidity and mortality. In turn, infections aggravate micronutrient deficiencies by reducing nutrient intake, increasing losses, and interfering with utilization by altering metabolic pathways. With aging a variety of changes are observed in the immune system, which translate into less effective innate and adaptive immune responses and increased susceptibility to infections. Antioxidant vitamins and trace elements (vitamins C, E, selenium, copper, and zinc) counteract potential damage caused by reactive oxygen species to cellular tissues and modulate immune cell function Adequate intake of vitamins B(6), folate, B(12), C, E, and of selenium, zinc, copper, and iron supports immune response with sufficient production of proinflammatory cytokines, which maintains an effective immune response and avoids a shift to an anti-inflammatory cell-mediated immune response and an increased risk of extracellular infections. Supplementation with these micronutrients reverses mediated immune response to a proinflammatory with enhanced innate immunity. Vitamins A and D play important roles in both cell-mediated and humoral antibody response and support an anti-inflammatory profile. Vitamin A deficiency impairs both innate immunity (mucosal epithelial regeneration) and adaptive immune response to infection resulting in an impaired ability to counteract extracellular pathogens. Vitamin D deficiency is correlated with a higher susceptibility to infections due to impaired localized innate immunity and defects in antigen-specific cellular immune response. Overall, inadequate intake and status of these vitamins and minerals may lead to suppressed immunity, which predisposes to infections.
FOR IMMEDIATE RELEASE
Orthomolecular Medicine News Service, Mar 22, 2020
Published Research and Articles on Vitamin C as a Consideration for Pneumonia, Lung Infections, and the Novel Coronavirus (SARS-CoV-2/COVID-19)
By Graham Player, PhD, Andrew W. Saul, Damien Downing, MBBS, MRSB and Gert Schuitemaker, PhD
ABSTRACT: Vitamin C supports your immune system. Vitamin C helps to kill viruses and reduces the symptoms of infection. It’s not a COVID-19 “cure,” but nothing is. Nothing is proven to work against COVID-19, because it is a new virus. Vitamin C has worked against every single virus including influenzas, pneumonia, and even poliomyelitis. In the medical literature, there are more than 64,000 published articles and studies on Vitamin C available at The U.S. National Library of Medicine National Center for Biotechnology Information . Vitamin C is arguably one of the most researched substances in existence.
Vitamin C is an essential micronutrient for humans. Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C deficiency results in impaired immunity and higher susceptibility to infections. It is a potent antioxidant and a cofactor for a family of biosynthetic and gene regulatory enzymes. Infections significantly impact on vitamin C levels due to enhanced inflammation and metabolic requirements. Furthermore, supplementation with vitamin C appears to be able to both prevent and treat respiratory and systemic infections.
Vitamin D is involved in immune function, disease prevention and is vital to several different aspects of health. Although it’s most well-known for its ability to strengthen the bones and boost calcium absorption, it alsoaffects mood regulation and weight control. A deficiency in this crucial vitamin can cause issues like hair loss, chronic pain, sluggishness and decreased wound healing. Research suggests the vitamin D may have numerous benefits related to cancer, muscle strength, and mental health.
Zinc, an essential nutrient, is required in numerous processes including immune function, gene expression, DNA and protein synthesis, and more. Zinc’s role in immune function is one reason why it is a popular natural cold treatment. Studies have shown that zinc supplements help keep the immune system strong. A metanalysis on the efficacy of zinc found that 80 to 92 milligrams per day of reduced the duration of the common cold by 33%. Additionally, it’s been shown that older adults taking zinc supplements significantly reduced the risk of infectious diseases and improve immune response. Zinc like many other nutrients, is not produced naturally by the body because of this it must be obtained from supplements or food.
Echinacea is best known for its positive effects on the immune system. Numerous studies have shown that this herb supports immune system function, reducing the risk of contracting viruses and infections. One study done reported that the immune system benefited from 10 milligrams of echinacea per one kilogram of body weight, taken every day over a 10-day period. A meta-analysis found that echinacea may decrease the risk of catching the common cold by more than 50% and reduce the duration by one and a half days. Echinacea is a popular herb used worldwide. These plants contain a variety of active compounds that function as antioxidants used to defend cells against oxidative stress, a state linked to various diseases.
Probiotics 70-80% of our entire immune system resides within the digestive system. When necessary, inflammation in the intestines creates a pathway for the immune system to carry out an attack against invading viruses and bacteria. However, when inflammation is present but not needed, illnesses such as chronic infections can occur. Probiotics can also modulate the immune system, enhancing the body’s innate immunity. This modulating effect helps alleviate excessive inflammation in the digestive system, thereby boosting immune function. Probiotics offer a beneficial defense against the effects caused by this unwarranted inflammation. Probiotics help keep the digestive system healthy, to ensure the immune system functions well. Epithelial tissues in the intestines form a barrier against pathogenic microbes and other harmful substances present. Probiotics foster intestinal epithelial cell survival, strengthen cell barrier function, and initiate protective responses
Immune C Liquid form for Children & Elderly Strong Antioxidant, Supports Healthy Immune System. Vitamin C is an antioxidant that helps support the immune system and helps neutralize free radicals in the body. Supplementation with vitamin C appears to be able to both aid in the prevention and treatment of respiratory and systemic infections. Vitamin C is an essential micronutrient for humans. It is a potent antioxidant and a cofactor for a family of biosynthetic and gene regulatory enzymes. Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system. Vitamin C deficiency results in impaired immunity and higher susceptibility to infections. In turn, infections significantly impact on vitamin C levels due to enhanced inflammation and metabolic requirements.